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The Mass General Research Institute promotes, supports and guides research at Massachusetts General Hospital. Massachusetts General Hospital is home to the largest hospital-based research enterprise in the U.S., with an annual budget of nearly $1.2 billion in 2021. The Mass General Research Institute comprises more than 9,500 researchers working across more than 30 institutes, centers and departments. As the oldest and largest teaching hospital of Harvard Medical School, Mass General has been a leader in bridging innovative science with highly advanced clinical care for more than 200 years. The Mass General Research Institute is built on a culture of excellence, compassion and groundbreaking scientific achievement. Our researchers work side-by-side with physicians—in the lab, in the clinic and at the bedside—harnessing the latest technological advancements to foster discovery at every stage.

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